منابع مشابه
Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation
Tumour cells may be resistant to radiotherapy that results in unsuccessful cancer treatment in patients. The aim of this study was to evaluate the sensitizing effect of atorvastatin (ATV) on breast cancer (MDA-MB-231) and non-small cell lung cancer (A-549) cells following exposure to ionizing radiation (IR). These cells were treated with ATV and exposed to X-ray at dose 4 Gy. The radiosensitizi...
متن کاملAtorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation
Tumour cells may be resistant to radiotherapy that results in unsuccessful cancer treatment in patients. The aim of this study was to evaluate the sensitizing effect of atorvastatin (ATV) on breast cancer (MDA-MB-231) and non-small cell lung cancer (A-549) cells following exposure to ionizing radiation (IR). These cells were treated with ATV and exposed to X-ray at dose 4 Gy. The radiosensitizi...
متن کاملIonizing radiation and cancer prevention.
Ionizing radiation long has been recognized as a cause of cancer. Among environmental cancer risks, radiation is unique in the variety of organs and tissues that it can affect. Numerous epidemiological studies with good dosimetry provide the basis for cancer risk estimation, including quantitative information derived from observed dose-response relationships. The amount of cancer attributable t...
متن کاملIonizing radiation, breast cancer, and ataxia-telangiectasia.
It is well established that genetic predisposition (/) and environmental exposure to ionizing radiation (2) each play an important role in the etiology of breast cancer. In this issue of the Journal, Lavin et al. (3) address the important possibility that some individuals are predisposed to breast cancer because they are more susceptible than the rest of the population to the carcinogenic effec...
متن کاملCaveolin-1, breast cancer and ionizing radiation.
Breast cancer (BC) recovery has increased in recent years thanks to efforts of Omics-based research in this field. However, despite the important results obtained, BC remains a complex multifactorial pathology that is difficult to treat appropriately. Caveolin-1 (CAV1), the basic constituent protein of specialized plasma membrane invaginations called caveolae, is emerging as a potential therape...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Critical Reviews™ in Oncogenesis
سال: 2018
ISSN: 0893-9675
DOI: 10.1615/critrevoncog.2018026412